A New Model for Orthopaedic Manual Therapy Research: Description and Implications

A new model for orthopaedic manual therapy research: description and implications.

Despite forays into editing, consulting, and teaching, I still consider myself first and foremost a clinician. And, at that, I like to think of myself as an evidence-based clinician. For me this appreciation of the importance of research in my day-to-day clinical decision-making did not come easy. My entry-level degree in physical therapy strongly emphasized authority-based knowledge and clinic...

What's new in orthopaedic research.

A Simulation-Based Optimization Model for Scheduling New Product Development Projects in Research and Development Centers

a simulation-based optimization approach for the purpose of finding a near-optimal answer can be efficient and effective. In the present paper, first, the mathematical model for the project activity scheduling problem has been presented with a job shop approach. Then, using the Arena 14 software, the simulation model has been designed. Consequently, a numerical example has been solved via runni...

The orthopaedic implications of diphosphonate therapy.

Diphosphonates are among the many commonly prescribed drugs for osteoporosis management. These synthetic analogues of physiologically occurring inorganic pyrophosphate bind to the hydroxyapatite crystals of bone. Diphosphonates act by decreasing the amount of osteoclast-mediated bone resorption by inducing apoptosis and disrupting the mevalonate biosynthetic pathway. Prospective clinical trials...

A SEGMENTED REGRESSION MODEL FOR DESCRIPTION OF MICROBIAL GROWTH

A segmented regression model for the description of microbial growth has been suggested. The model is able to predict the exponential growth, logistic growth, logistic growth with a phase of decline, diauxic growth, microbial growth in synchronous cultures and the oscillatory growth